GRE over IPsec is a technology for encrypting and encapsulating packets that cannot be encrypted or encapsulated by IPsec, such as multicast and broadcast packets. IPsec is used for encrypting and encapsulating IP packets only.
IPsec applies only to IPv4 unicast packets. To cover IPv6 unicast, IPv4 multicast, IPv4 broadcast, and L2VPN/L3VPN IPv4 packets, configure IPv6 over GRE over IPsec.